Polysialic acid bioengineering of neuronal cells by N-acyl sialic acid precursor treatment
نویسندگان
چکیده
منابع مشابه
Polysialic acid bioengineering of neuronal cells by N-acyl sialic acid precursor treatment.
The inherent promiscuity of the polysialic acid (PSA) biosynthetic pathway has been exploited by the use of exogenous unnatural sialic acid precursor molecules to introduce unnatural modifications into cellular PSA, and has found applications in nervous system development and tumor vaccine studies. The sialic acid precursor molecules N-propionyl- and N-butanoyl-mannosamine (ManPr, ManBu) have b...
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ژورنال
عنوان ژورنال: Glycobiology
سال: 2006
ISSN: 1460-2423,0959-6658
DOI: 10.1093/glycob/cwl075